Tesamorelin is a synthetic peptide that mimics the action of growth hormone-releasing hormone (GHRH). It's primarily used to treat lipodystrophy in HIV patients, a condition characterized by abnormal fat distribution. Here are some key points about Tesamorelin:
What is Tesamorelin?
Function: Stimulates the release of growth hormone (GH) from the pituitary gland.
Brand Names: Sold under the brand name Egrifta SV.
Uses
Lipodystrophy: Reduces excess abdominal fat in HIV patients taking antiretroviral therapy.
Growth Hormone Deficiency: May be used off-label to treat growth hormone deficiency in adults.
Benefits
Fat Reduction: Helps reduce visceral fat around the stomach.
Improved Body Composition: Can lead to a more favorable body composition by reducing fat and increasing lean muscle mass.
Dosage and Administration
Form: Subcutaneous injection.
Typical Dosage: Usually administered as a 2 mg injection once daily.
Side Effects
Common Side Effects: Nausea, vomiting, diarrhea, and injection site reactions.
Serious Side Effects: Swelling in extremities, joint pain, and high blood sugar.
Precautions
Pregnancy: Not recommended for use during pregnancy.
Medical History: Should be used with caution in individuals with a history of tumors, head injuries, or radiation treatment
Tesamorelin
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