MK-677, also known as Ibutamoren, is a growth hormone secretagogue that mimics the action of the hunger hormone ghrelin. Here are some key points about MK-677:
What is MK-677?
Function: MK-677 stimulates the release of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) from the pituitary gland.
Benefits: Increased GH and IGF-1 levels can promote muscle growth, fat loss, improved recovery, and overall metabolic health.
Mechanism of Action
Growth Hormone Release: By binding to the growth hormone secretagogue receptor (GHS-R1a), MK-677 increases GH levels with minimal impact on other hormones like cortisol.
IGF-1 Production: Enhances the production of IGF-1, which supports muscle growth and tissue repair.
Potential Benefits
Muscle Growth: Promotes lean muscle mass and strength.
Fat Loss: Helps reduce body fat.
Improved Recovery: Enhances muscle recovery and reduces soreness.
Anti-Aging Effects: May contribute to delaying the aging process by boosting natural GH production.
Dosage and Usage
Typical Dosage: Dosage can vary, but common doses include 10 mg to 25 mg per day.
Administration: Taken orally, making it more convenient than injectable peptides.
Side Effects
Mild Side Effects: Can include headaches, nausea, and increased appetite2.
Serious Side Effects: Potential for increased blood glucose levels, decreased insulin sensitivity, and bone mineral density reduction.
Long-Term Use: The long-term effects are not well-studied, and it's important to consult with a healthcare professional before starting any new treatment.
Important Considerations
Not FDA-Approved: MK-677 is still considered experimental and is not approved for human use in many countries.
Banned in Sports: Prohibited in competitive sports by organizations like WADA due to potential health risks and performance-enhancing effects
MK 677
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